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  1. Efficacy of Bempedoic Acid, Novel Treatment for Elevated LDL Cholesterol

    Feb 17, 2025 · By Anthony Rice Bempedoic acid is a novel non-statin drug produced by Esperion Therapeutics to treat hypercholesterolemia, elevated levels of low-density lipoprotein (LDL) …

  2. Reshaping Dyslipidaemia Treatment with Bempedoic Acid—A ... - MDPI

    Jun 12, 2025 · Apolipoprotein B, total cholesterol, and non-HDL-C were also reduced, particularly in the combination therapy, while hsCRP was reduced particularly in the monotherapy group with 180 mg …

  3. Bempedoic Acid: The Statin Alternative for Lowering Cholesterol

    Jun 12, 2025 · Learn how bempedoic acid lowers cholesterol without the muscle side effects of statins. See who it's for, how it works, and clinical trial results.

  4. Comparative Cardiovascular Benefits of Bempedoic Acid and Statin …

    Jul 1, 2024 · Background In the CLEAR (Cholesterol Lowering via Bempedoic Acid, an ACL-Inhibiting Regimen) Outcomes trial, treatment of statin-intolerant patients with bempedoic acid produced a …

  5. Comprehensive review of statin-intolerance and the practical ...

    Nov 14, 2023 · Bempedoic acid (BA), an ATP citrate lyase inhibitor, decreases hepatic generation of cholesterol, upregulates low-density lipoprotein (LDL) receptor expression in the liver, and eventually …

  6. Expert opinion on the integration of combination therapy into the ...

    Mar 6, 2025 · A multidisciplinary expert panel convened to propose treatment algorithms to support this treatment approach in patients at high and very high CV risk. The experts completed a questionnaire …

  7. Use of bempedoic acid for LDL cholesterol lowering and …

    Feb 1, 2023 · This paper from the Italian Study Group on Atherosclerosis, Thrombosis and Vascular Biology summarizes current recommendations for treatment of hypercholesterolemia, barriers to lipid …

  8. Bempedoic Acid - StatPearls - NCBI Bookshelf

    Bempedoic acid is a lipid-lowering agent pivotal in managing patients with elevated low-density lipoprotein cholesterol (LDL-C) levels. The U.S. Food and Drug Administration (FDA) has sanctioned …

  9. (PDF) Bempedoic Acid: A Novel Approach in Managing

    Sep 28, 2024 · This review concludes that bempedoic acid represents a significant advancement in lipid-lowering therapy, offering a valuable option for patients with hypercholesterolemia, particularly those …

  10. CLEAR Outcomes: Similar CV Risk Reduction With Bempedoic Acid

    Nov 7, 2025 · Bempedoic acid is similar with statin therapy at decreasing the risk of a first major vascular event per every 1 mmol/L reduction in LDL-C, according to a post hoc analysis of the …